兰州大学药学院导师介绍：薛伟华

姓名：薛伟华   ( 男 ) 
职称职务：副教授
电子邮箱：xuewh@lzu.edu.cn

1、 学习与工作经历

2003年9月--2006年7月在南京大学生物化学专业学习，获博士学位

2006年7月-2007年7月 在加拿大阿尔伯特大学访问学习

2007年6月--2009年8月在海中国科学院上海有机化学研究所工作

2009年9月-现在  在兰州大学工作

2、教学工作与成果

讲授分析化学和物理化学

3、科研项目与成果

1. Weihua Xue, Huajia Diao, Xi Chen, Jiangning Chen and Junfeng Zhang. An efficient vector for gene delivery: α, β-poly (3-dimethylaminopropyl-D, L-aspartamide), European Journal of Pharmaceutics and Biopharmaceutics 2007 (66)327-333.

2. Weihua Xue, Xiaoyun Cheng, Jian Fan, Huajia Diao, Chunming Wang, Yi Luo, Jiangning Chen  and Junfeng Zhang. A novel stereoselective synthesis of 1, 2-trans-thioaldoses, Tetrahedron Letter 2007 (48) 6092-6095.

3. Weihua Xue, Jiansong Sun and Biao Yu. An efficient route to 2-amnio-β-galactosides and -glucosides via stereoselective Michael Addition of 2-nitrogalactal. Journal of organic Chemistry 2010 (74)5079-5082.

4. Weihua Xue,* Lifen Zhang. An Improved and Alternative Method for the Preparation of Per (6-bromo-6-deoxy)cyclodextrins. Synthesis, 2011, 3612–3614

5. Weihua Xue,* Lifen Zhang. A Novel Protocol for the Regioselective Bromination of Primary Alcohols in Unprotected Carbohydrates or Glycosides. Chinese journal of Chemistry, 2012(30)1429-1432

6. Weihua Xue,* Lifen Zhang. B (C6F5)3 as a Highly Effective Catalyst for the Phosphoryl Transfer Reaction.Chinese journal of Chemistry, 2012(30)1997-1800

7. Xiaofeng Liu, Sen Cheng, Xiaolei Wang, Weihua Xue*. A convenient procedure for the formation of per (6-deoxyl-6-halo)cyclodextrins using the combination of tetraethylammonium halide with [Et2NSF3]BF4. Synthesis, 2013, 45, 3103-3105.

8. Xiaolong Yuan, Sen Cheng, Yanbin Shi, Weihua Xue*. Photocatalytic synthesis of glycosyl bromide. Synthesis, 2014, 331-335

9. Lan Yu, Weihua Xue, Cui Lei, Hongyu Li. Use of hydroxypropyl-β-cyclodextrin/polyethylene glycol 400, modified Fe3O4 nanoparticles for congo red removal. International journal biological macromolecules. 2014, 64, 233-239.

10.  Dabo Pan, Weihua Xue, Xiaoting Wang, Jingjing Guo, Huanxiang Liu, Xiaojun Yao. Molecular Mechanism of the Enhanced Virulence of 2009 Pandemic Influenza A (H1N1) Virus from D222G Mutation in the Hemagglutinin: A Molecular Modeling Study. Journal of Molecular Modeling, 2012, 18,4355-4366.

11.  Xiaoyun Cheng, Weihua Xue, Huajia Diao and Junfeng Zhang.  Antitumor activity and toxicological properties of Doxorubicin conjugated to α, β-poly [(2-hydroxyethyl)-L-aspartamide] administrated intraperitoneally in mice. Anticancer Drug 2010(21)362-372.

4、研究与招生方向

糖化学和糖生物学